This post is the third in a six-part series taken from the article by Keith Wassung entitled “Diabetes and Chiropractic”.  This series focuses on diabetes as a disease,  treatments for diabetes, and the ways chiropractic care can help. Last week’s post explained both traditional and new treatments available for diabetics. This week’s post explains how diabetes impacts the body’s signaling systems. 

Part 3: Diabetes and Signaling

Recent advances in the fields of molecular biology and neuro-endocrinology have revealed that insulin deficiency may be due to a breakdown in the communication and signaling mechanisms associated with the central nervous system and metabolism.


Diagram of interaction between the gut and pancreas

“Intracellular and intercellular are the basic mechanisms for the regulation of all cells. Disturbances in cell signaling are central to disturbances in insulin secretion and action, which lead to diabetes and to both microand macrovascular complications.”1
American Diabetes Association




diagram explaining insulin resistance


“Insulin receptors and insulin signaling proteins are widely distributed throughout the central nervous system. New evidence now indicates that insulin participates in the central nervous system control of food intake and body weight, and the stage is now set for studies to determine if impaired central nervous system signaling contributes to the pathogenesis of two common metabolic diseases, obesity and type-2 diabetes.” 2
Science Week



Health care is slowly changing its focus from treatment of metabolic disorders with drugs and chemicals to shifting towards procedures that restore and maintain the normal communication and control systems of the human body.


Next week’s article will explain more about the relationship between diabetes and signaling by diving deeper into the topic of metabolism and the central nervous system. Stay tuned!



1. American Diabetes Organization,
2. Science Week Abstracts, Dec.8,2000